Optic neuritis presents with monocular vision loss.
Monocular vision loss has been shown to be treated with phlebotomy /
bloodletting.
Monocular vision loss is caused by the hyperviscosity of the blood.
Multiple sclerosis presents with .. optic neuritis .. AND is
accompanied by .. hyperviscosity.
Coincidence .. of .. course.
<<snip>>
due to the great viscosity of blood
<<snip>>
J Neurol Sci. 2007 Apr 25; [Epub ahead of print] Links
Isolated monocular visual loss as an initial manifestation of
polycythemia vera.Ahn BY, Choi KD, Choi YJ, Jea SY, Lee JE.
Department of Neurology, Pusan National University Hospital, Pusan
National University School of Medicine and Medical Research
Institute,
Republic of Korea.
A 25-year-old man developed prolonged loss of vision in the left eye.
Examination revealed that visual acuity was 20/20 in the right eye
and
10/20 in the left eye, with a left relative afferent pupillary
defect.
Fundoscopy showed multiple cotton wool spots in the left whole retina
with normal optic disc. Fluorescein angiography (FA) revealed
markedly
delayed arterial, venous and recirculation time in the left eye
without retinal arterial or venous occlusion. Bone marrow aspirate
confirmed polycythemia vera. After the patient underwent phlebotomy,
his visual acuity markedly improved and cotton wool spots in the
retina disappeared. On follow-up FA, delayed arterial and venous
filling, and recirculation time also became normalized. This case
suggests that ischemic damage of the retina due to the great
viscosity
of blood may be a possible mechanism of monocular visual loss in
polycythemia vera. Clinicians should be aware that isolated monocular
visual loss may be an initial manifestation of polycythemia vera,
since if untreated, polycythemia vera carries a high risk of
permanent
complications due to intravascular thrombosis.
PMID: 17466335 [PubMed - as supplied by publisher]
Rev Neurol Dis. 2006 Spring;3(2):45-56. Links
The natural historyof optic neuritis.Atkins EJ, Biousse V, Newman NJ.
Department of Neurology, University of Saskatchewan, Saskatoon, SK,
Canada.
Optic neuritis is a common cause of visual loss in young patients,
typically presenting with painful monocular visual loss and decreased
color vision. Visual function generally spontaneously improves over
weeks, and 95% of patients return to visual acuity of at least 20/40
within 12 months. The initial magnetic resonance imaging (MRI) helps
stratify the risk of multiple sclerosis (MS) in patients with acute
isolated optic neuritis. In the Optic Neuritis Treatment Trial, the 10-
year risk of MS in the group of patients with at least one MRI T2
lesion was 56%, whereas the 10-year risk with a normal baseline MRI
was 22%. A normal MRI in concert with painless optic neuritis, severe
optic nerve head edema, peripapillary hemorrhages, or a macular star
defines a very low MS risk subgroup. High-dose steroids hasten the
rate, but not the final extent, of visual recovery in optic neuritis,
and the decision to use this therapy is individualized. Interferon
beta-1a therapy should be considered in selected high-risk patients.
PMID: 16819420 [PubMed - in process]
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