Can I dilute Lotemax to make Alrex?

Discussion in 'Optometry Archives' started by shawroom_124_youknow, Jul 22, 2007.

  1. Hi, my eye doctor changes my prescription to Alrex one week after she
    wrote me a big bottle of Lotemax. Can I simply add over the counter
    saline drops to Lotemax to make Alrex?

    shawroom_124_youknow, Jul 22, 2007
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  2. shawroom_124_youknow

    p.clarkii Guest

    steroid preps like Lotemax/Alrex are actually suspensions. the
    steroid is not completely dissolved in the buffer but instead is
    suspended in the solution in small particles. creating a suspension
    is a little tricky because if the buffer conditions are not correct
    the steroid will precipitate out in the bottom of the bottle. i don't
    think it would work out for you successfully if you tried diluting
    with saline (or anything else unless you knew the exact pH, salt
    conc., etc.).

    nice idea but I'd recommend against it.
    p.clarkii, Jul 23, 2007
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  3. Thank you.
    shawroom_124_youknow, Jul 23, 2007
  4. You probably could, but you'd have to use sterile technique and you
    would dilute the preservatives and buffers so all bets are off on the

    w.stacy, o.d.
    William Stacy, O.D., Jul 30, 2007
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